Phase-field model for the morphology of monolayer lipid domains

Year: 2012
Keywords: Biological Physics, Biomimetic Systems
  • Campelo, F.
  • Cruz, A.
  • Pérez-Gil, J.
  • Vázquez, L.
  • Hernández-Machado, A.
Journal: European Physical Journal E Volume: 35
Number: 6
ISSN: 1292-8941
Phase-separated domains exist in multicomponent lipid monolayers and bilayers. We present here a phase-field model that takes into account the competition between lipid dipole-dipole interactions and line tension to define the domain morphology. A dynamic equation for the phase-field is solved numerically showing stationary non-circular shapes like starfish shapes. This phase-field model could be applied to study the dynamic properties of complex problems like phase segregation in pulmonary surfactant membranes and films.
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